The Oct2 protein, encoded by the Pou2f2 gene, was originally predicted to act as a DNA binding transcriptional activator of immunoglobulin (Ig) in B lineage cells.This prediction flowed from the earlier observation that an 8 bp sequence, the octamer motif, was a highly conserved component of most Ig gene promoters and enhancers, and evidence from o
Abstract In human walking, the left and right legs move alternately, half a stride out of phase with each other.Although various parameters, such as stride frequency and length, vary with walking speed, the antiphase relationship remains unchanged.In contrast, during walking in left-right asymmetric situations, the relative phase shifts from the an
In this paper I outline the main features of the phenomenological approach, focusing on the central themes of intentionality, embodiment, empathy, intersubjectivity, sociality and the life-world.I argue that phenomenology is primarily a philosophy of intentional explication that identifies the a priori, structural correlations between subjectivity
The mechanisms by which aging and other processes can affect the structure and function of brain networks are important to understanding southwestern aztec rug normal age-related cognitive decline.Advancing age is known to be associated with various disease processes, including clinically asymptomatic vascular and inflammation processes that contri
IntroductionExtracellular vesicles (EVs) and particles (EPs) represent reliable biomarkers aptamil allerpro for disease detection.Their role in the inflammatory microenvironment of severe COVID-19 patients is not well determined.Here, we characterized the immunophenotype, the lipidomic cargo and the functional activity of circulating EPs from sever